Product Overview
CCT367766 | T14908 | TargetMol Chemicals
CAS: 2229856-58-8
Smiles: Clc1ccc(NC(=O)c2ccc3OCCOc3c2)cc1NC(=O)c1ccc2nc(CN3CCN(CCOCCOCCOc4cccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c45)CC3)ccc2c1
Formula: C49H48ClN7O11
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: CCT367766 is the PROTAC-based pirin targeting protein degradation probe, depletes pirin protein expression at low concentration. It shows a moderate affinity for the CRBN-DDB1 complex (IC50: 490 nM). CCT367766 reveals a good affinity for the recombinant pirin and CRBN (Kds: 55 nM and 120 nM).
Molecular Weight: 946, 41