Product Overview
CDK2-IN-4 | T14916 | TargetMol Chemicals
CAS: 2079895-42-2
Smiles: NS(=O)(=O)c1ccc(Nc2nc(-c3cccc(c3)-c3ccccc3)c3nc[nH]c3n2)cc1
Formula: C23H18N6O2S
Pathway: Cell Cycle/Checkpoint
Target: CDK
Receptor: N/A
Bioactivity: CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A. It shows 2, 000-fold selectivity over CDK1/cyclin B with IC50 of 86 uM.
Molecular Weight: 442, 5