Product Overview
CE-245677 | T14921 | TargetMol Chemicals
CAS: 717899-97-3
Smiles: COc1ccc(cc1NC(=O)Nc1ccc(Cl)cc1Cl)C(=O)c1cn(C(C)C)c2ncnc(N)c12
Formula: C24H22Cl2N6O3
Pathway: Tyrosine Kinase/Adaptors
Target: Tie-2|||Trk receptor
Receptor: N/A
Bioactivity: CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases. With a cellular IC50s of 4.7 and 1 nM.
Molecular Weight: 513, 38
