Product Overview
Cenisertib | T14925 | TargetMol Chemicals
CAS: 871357-89-0
Smiles: [H][C@@]12C[C@@]([H])(C=C1)[C@@H]([C@@H]2Nc1nc(Nc2ccc(N3CCN(C)CC3)c(C)c2)ncc1F)C(N)=O
Formula: C24H30FN7O
Pathway: Angiogenesis|||Cytoskeletal Signaling|||JAK/STAT signaling|||PI3K/Akt/mTOR signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: Akt|||Bcr-Abl|||STAT
Receptor: N/A
Bioactivity: Cenisertib (AS-703569) is a multi-kinase inhibitor and blocks the activity of Aurora-kinase-A/B, AKT, ABL1, STAT5, and FLT3. Cenisertib inhibits tumor growth in xenograft models of breast, pancreatic, ovarian, colon, lung tumors, and leukemia.
Molecular Weight: 451, 55