Cenisertib | T14925

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€535.00 - €2,873.00
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TMC-T14925
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Product Overview

Cenisertib | T14925 | TargetMol Chemicals

CAS: 871357-89-0

Smiles: [H][C@@]12C[C@@]([H])(C=C1)[C@@H]([C@@H]2Nc1nc(Nc2ccc(N3CCN(C)CC3)c(C)c2)ncc1F)C(N)=O

Formula: C24H30FN7O

Pathway: Angiogenesis|||Cytoskeletal Signaling|||JAK/STAT signaling|||PI3K/Akt/mTOR signaling|||Stem Cells|||Tyrosine Kinase/Adaptors

Target: Akt|||Bcr-Abl|||STAT

Receptor: N/A

Bioactivity: Cenisertib (AS-703569) is a multi-kinase inhibitor and blocks the activity of Aurora-kinase-A/B, AKT, ABL1, STAT5, and FLT3. Cenisertib inhibits tumor growth in xenograft models of breast, pancreatic, ovarian, colon, lung tumors, and leukemia.

Molecular Weight: 451, 55

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