Product Overview
Cerdulatinib hydrochloride | T6104 | TargetMol Chemicals
CAS: 1369761-01-2
Smiles: Cl.CCS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Formula: C20H28ClN7O3S
Pathway: Angiogenesis|||Chromatin/Epigenetic|||JAK/STAT signaling|||MAPK|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: MLK|||c-Fms|||Tyrosine Kinases|||Hippo pathway|||JAK|||Syk
Receptor: N/A
Bioactivity: Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.
Molecular Weight: 482
