Product Overview
CGP-28014 | T26997 | TargetMol Chemicals
CAS: 111757-17-6
Smiles: CCCN(CCC)\C=N\c1cccc(=O)[nH]1
Formula: C12H19N3O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: CGP-28014 is an inhibitor of catechol-O-methyltransferase. CGP-28014 increases the renal excretion of both dopamine and dihydroxyphenylacetic acid (DOPAC) but does not affect renal sodium handling indicating a different mechanism of action. CGP-28014 significantly reduced the levels of homovanillic acid (HVA), but did not modify DA and 3, 4-dihydroxyphenylacetic acid (DOPAC).
Molecular Weight: 221, 304