CGP-28014 | T26997

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TMC-T26997
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Product Overview

CGP-28014 | T26997 | TargetMol Chemicals

CAS: 111757-17-6

Smiles: CCCN(CCC)\C=N\c1cccc(=O)[nH]1

Formula: C12H19N3O

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: CGP-28014 is an inhibitor of catechol-O-methyltransferase. CGP-28014 increases the renal excretion of both dopamine and dihydroxyphenylacetic acid (DOPAC) but does not affect renal sodium handling indicating a different mechanism of action. CGP-28014 significantly reduced the levels of homovanillic acid (HVA), but did not modify DA and 3, 4-dihydroxyphenylacetic acid (DOPAC).

Molecular Weight: 221, 304

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