Product Overview
CGP60474 | T14943 | TargetMol Chemicals
CAS: 164658-13-3
Smiles: OCCCNc1cc(ccn1)-c1ccnc(Nc2cccc(Cl)c2)n1
Formula: C18H18ClN5O
Pathway: Angiogenesis|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: VEGFR|||CDK|||PKC
Receptor: N/A
Bioactivity: CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently.
Molecular Weight: 355, 83
