Product Overview
Chamigrenal | T3P2855 | TargetMol Chemicals
CAS: 19912-84-6
Smiles: CC1(C)CCCC(=C)C11CCC(C=O)=CC1
Formula: C15H22O
Pathway: Angiogenesis|||GPCR/G Protein|||Immunology/Inflammation|||JAK/STAT signaling|||Neuroscience|||Tyrosine Kinase/Adaptors
Target: EGFR|||NOS|||PAFR|||COX|||Prostaglandin Receptor
Receptor: N/A
Bioactivity: β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 macrophages. Chamigrenal shows platelet-activating factor antagonistic activity and the IC(50) value of 1.2x10(-4) M; it also exhibits weak cytotoxicity towards MCF-7 cells(IC50=30.50 uM).
Molecular Weight: 218, 34