Product Overview
Chiauranib | T35570 | TargetMol Chemicals
CAS: 1256349-48-0
Smiles: N/A
Formula: C27H21N3O3
Pathway: Angiogenesis|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors
Target: c-Fms|||VEGFR|||FLT|||PDGFR|||c-Kit|||Aurora Kinase
Receptor: N/A
Bioactivity: Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-related kinase Aurora B, and chronic inflammation-related kinase CSF1R, with IC50 values ranging from 1-9 nM.
Molecular Weight: 435, 47