Product Overview
CHS-111 | T27013 | TargetMol Chemicals
CAS: 886755-63-1
Smiles: OCc1ccc(cc1)-c1n(Cc2ccccc2)nc2ccccc12
Formula: C21H18N2O
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: CHS-111 is a benzyl indazole compound. CHS-111 inhibits superoxide anion (O(2)(-)) generation. CHS-111 reduces the fMLP-stimulated PLD activity (IC(50) 3.9±1.2μM). CHS-111 inhibits the interaction of PLD1 with ADP-ribosylation factor (Arf) 6 and Ras homology (Rho) A, and reduces the membrane recruitment of RhoA in fMLP-stimulated cells.
Molecular Weight: 314, 388
