Product Overview
Ciclopirox | T1482 | TargetMol Chemicals
CAS: 29342-05-0
Smiles: Cc1cc(C2CCCCC2)n(O)c(=O)c1
Formula: C12H17NO2
Pathway: Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||Membrane transporter/Ion channel|||Microbiology/Virology
Target: ATPase|||Ferroptosis|||Antibacterial|||Autophagy|||Antifungal
Receptor: N/A
Bioactivity: Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. Ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, the organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX).
Molecular Weight: 207, 273
