Product Overview
Cilengitide TFA | T6806 | TargetMol Chemicals
CAS: 199807-35-7
Smiles: OC(=O)C(F)(F)F.CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O
Formula: C29H41F3N8O9
Pathway: Autophagy|||Cytoskeletal Signaling
Target: Integrin|||Autophagy
Receptor: N/A
Bioactivity: Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.
Molecular Weight: 702, 689
