Ciluprevir | T19627

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TMC-T19627
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Product Overview

Ciluprevir | T19627 | TargetMol Chemicals

CAS: 300832-84-2

Smiles: [H][C@@]12C[C@]1(NC(=O)[C@]1([H])C[C@H](CN1C(=O)[C@H](CCCCC\C=C/2)NC(=O)OC1CCCC1)Oc1cc(nc2cc(OC)ccc12)-c1csc(NC(C)C)n1)C(O)=O

Formula: C40H50N6O8S

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: Ciluprevir is an effective and selective HCV NS3 protease inhibitor with proven antiviral effect in humans. Ciluprevir may be an antiviral agent for individuals infected with non-genotype-1 HCV. In vitro sensitivity studies with Ciluprevir showed a decrease in affinity for proteases of genotypes 2 and 3 (Ki: 80 to 90 nM) compared to genotype 1 enzymes (Ki: 1.5 nM).

Molecular Weight: 774, 93

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