Product Overview
Ciluprevir | T19627 | TargetMol Chemicals
CAS: 300832-84-2
Smiles: [H][C@@]12C[C@]1(NC(=O)[C@]1([H])C[C@H](CN1C(=O)[C@H](CCCCC\C=C/2)NC(=O)OC1CCCC1)Oc1cc(nc2cc(OC)ccc12)-c1csc(NC(C)C)n1)C(O)=O
Formula: C40H50N6O8S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Ciluprevir is an effective and selective HCV NS3 protease inhibitor with proven antiviral effect in humans. Ciluprevir may be an antiviral agent for individuals infected with non-genotype-1 HCV. In vitro sensitivity studies with Ciluprevir showed a decrease in affinity for proteases of genotypes 2 and 3 (Ki: 80 to 90 nM) compared to genotype 1 enzymes (Ki: 1.5 nM).
Molecular Weight: 774, 93