Product Overview
CITCO | T14973 | TargetMol Chemicals
CAS: 338404-52-7
Smiles: Clc1ccc(cc1)-c1nc2sccn2c1\C=N\OCc1ccc(Cl)c(Cl)c1
Formula: C19H12Cl3N3OS
Pathway: Apoptosis|||Others
Target: Apoptosis|||Others
Receptor: N/A
Bioactivity: CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. CITCO is an imidazothiazole derivative and it also is a selective Constitutive androstane receptor (CAR) agonist.
Molecular Weight: 436, 74
