Product Overview
CJ-15208 | T27027 | TargetMol Chemicals
CAS: 210236-47-8
Smiles: O=C1N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@H]12
Formula: C34H35N5O4
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: CJ-15208 is a potent and selective κ-opioid receptor antagonist from a fungus, Ctenomyces serratus ATCC15502 (IC50 are 47 nM for kappa, 260 nM for mu, and 2, 600 nM for delta respectly). In the electrically-stimulated twitch response assay of rabbit vas deferens, CJ-15208 recovered the suppression by a kappa agonist asimadoline with an ED50 of 1.3 microM.
Molecular Weight: 577, 685
