Product Overview
CJ-42794 | T14975 | TargetMol Chemicals
CAS: 847728-01-2
Smiles: C[C@H](NC(=O)c1cc(Cl)ccc1Oc1ccc(F)cc1)c1ccc(cc1)C(O)=O
Formula: C22H17ClFNO4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: CJ-42794 is a selective antagonist of prostaglandin E receptor subtype 4 (EP4). It inhibits [3H]-PGE2 binding to the human EP4 receptor (a mean pKi: 8.5). CJ-42794 is a binding affinity that was at least 200-fold more selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3) (IC50 : 8.5 (pKi )).
Molecular Weight: 413, 83
