CK1-IN-1 | T5393

CK1-IN-1 | T5393 | TargetMol Chemicals

CAS: 1784751-20-7

Smiles: Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1ccc2ccccc2c1F

Formula: C24H15F2N3

Pathway: MAPK|||Metabolism|||Stem Cells

Target: p38 MAPK|||Casein Kinase

Receptor: N/A

Bioactivity: CK1-IN-1, compound 1c reported in patent WO2015119579A1, is a casein kinase 1 (CK1) inhibitor. It has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively.

Molecular Weight: 383, 402