Product Overview
CKI-7 | T19913 | TargetMol Chemicals
CAS: 1177141-67-1
Smiles: Cl.Cl.NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12
Formula: C11H14Cl3N3O2S
Pathway: Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||MAPK|||Metabolism|||PI3K/Akt/mTOR signaling|||Stem Cells
Target: ROCK|||SGK|||Casein Kinase|||CDK|||S6 Kinase
Receptor: N/A
Bioactivity: CKI-7 2HCl is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 2HCl also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
Molecular Weight: 358, 66
