Product Overview
CL-387785 | T2245 | TargetMol Chemicals
CAS: 194423-06-8
Smiles: CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
Formula: C18H13BrN4O
Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: EGFR
Receptor: N/A
Bioactivity: CL-387785(EKI785; WAY-EKI 785) is an irreversible inhibitor of EGFR（IC50： 370+/-120 pM）; is able to overcome resistance caused by the T790M mutation on a functional level.
Molecular Weight: 381, 233
