Product Overview
CL2A | T17732 | TargetMol Chemicals
CAS: 1846605-04-6
Smiles: NCCCC[C@H](NC(=O)COCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCn1cc(CNC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)nn1)C(=O)Nc1ccc(COC(O)=O)cc1
Formula: C51H79N9O18
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: CL2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker[1].
Molecular Weight: 1106, 238
