Product Overview
Clofarabine | T0297 | TargetMol Chemicals
CAS: 123318-82-1
Smiles: Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F
Formula: C10H11ClFN5O3
Pathway: Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Target: Apoptosis|||Nucleoside Antimetabolite/Analog|||DNA/RNA Synthesis|||Autophagy
Receptor: N/A
Bioactivity: Clofarabinem, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
Molecular Weight: 303, 68
