Product Overview
CMP3a | T27052 | TargetMol Chemicals
CAS: 2225902-88-3
Smiles: C[C@@H](Oc1cc(sc1C(N)=O)-c1cnc2cc(ccn12)-c1cnn(CCN(C)C)c1)c1ccccc1C(F)(F)F
Formula: C28H27F3N6O2S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.
Molecular Weight: 568, 62