Product Overview
CMS-121 | T14991 | TargetMol Chemicals
CAS: 1353224-53-9
Smiles: Oc1ccc(cc1O)-c1cc(OC2CCCC2)c2ccccc2n1
Formula: C20H19NO3
Pathway: Metabolism
Target: Acetyl-CoA Carboxylase
Receptor: N/A
Bioactivity: CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activities.
Molecular Weight: 321, 376
