Product Overview
COH000 | T5199 | TargetMol Chemicals
CAS: 1534358-79-6
Smiles: [H][C@]12O[C@@](C=C1)([C@@H](Cc1ccc(C)cc1)Nc1ccccc1)C(C(=O)OC)=C2C(=O)OC
Formula: C25H25NO5
Pathway: Ubiquitination
Target: E1/E2/E3 Enzyme
Receptor: N/A
Bioactivity: COH000 is a covalent and irreversible inhibitor of small ubiquitin-like modifier (SUMO)-activating enzyme and inhibited SUMOylation (IC50: ~ 0.2 μM in vitro).
Molecular Weight: 419, 477