Product Overview
Corosolic acid | T3391 | TargetMol Chemicals
CAS: 4547-24-4
Smiles: C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O
Formula: C30H48O4
Pathway: Angiogenesis|||Autophagy|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: FAK|||Autophagy
Receptor: N/A
Bioactivity: Corosolic acid contains anti-angiogenic activity that can suppress FAK signaling induced by angiopoietin-1. Corosolic acid exerts anticancer activities against HCC, colon, and colorectal Y cells, by inducing apoptosis and promoting the N-terminal phosphorylation and subsequent proteasomal degradation of β-catenin.
Molecular Weight: 472, 71
