Product Overview
Crenolanib | T2677 | TargetMol Chemicals
CAS: 670220-88-9
Smiles: CC1(COc2ccc3n(cnc3c2)-c2ccc3cccc(N4CCC(N)CC4)c3n2)COC1
Formula: C26H29N5O2
Pathway: Angiogenesis|||Autophagy|||Tyrosine Kinase/Adaptors
Target: FLT|||PDGFR|||Autophagy
Receptor: N/A
Bioactivity: Crenolanib is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).
Molecular Weight: 443, 551