Product Overview
Cridanimod sodium | T5317L | TargetMol Chemicals
CAS: 58880-43-6
Smiles: O=C([O-])CN(C1=C2C=CC=C1)C3=CC=CC=C3C2=O.[Na+]
Formula: C15H10NNaO3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Cridanimod can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Cridanimod is able to induce the expression of PR in endometrial cancer. In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen released from the ovaries.
Molecular Weight: 275, 23