Product Overview
CTPI-2 | T8732 | TargetMol Chemicals
CAS: 68003-38-3
Smiles: OC(=O)c1ccccc1NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O
Formula: C13H9ClN2O6S
Pathway: Metabolism|||Others
Target: Others|||Mitochondrial Metabolism
Receptor: N/A
Bioactivity: CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet.
Molecular Weight: 356, 73
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