Product Overview
Curcumin | T1516 | TargetMol Chemicals
CAS: 458-37-7
Smiles: COc1cc(ccc1O)\C=C\C(=O)CC(=O)\C=C\c1ccc(O)c(OC)c1
Formula: C21H20O6
Pathway: Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Microbiology/Virology|||Others
Target: Mitophagy|||Others|||Epigenetic Reader Domain|||Ferroptosis|||Influenza Virus|||Histone Acetyltransferase|||Autophagy
Receptor: N/A
Bioactivity: Curcumin is a phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as turmeric, with a variety of pharmacologic properties. Curcumin blocks the formation of reactive oxygen species, possesses anti-inflammatory properties as a result of inhibition of cyclooxygenases (COX) and other enzymes involved in inflammation; and disrupts cell signal transduction by various mechanisms including inhibition of protein kinase C. These effects may play a role in the agent's observed antineoplastic properties, which include inhibition of tumor cell proliferation and suppression of chemically induced carcinogenesis and tumor growth in animal models of cancer.
Molecular Weight: 368, 39
