Product Overview
CVT-10216 | T15022 | TargetMol Chemicals
CAS: 1005334-57-5
Smiles: CS(=O)(=O)Nc1ccc(cc1)-c1coc2cc(OCc3cccc(c3)C(O)=O)ccc2c1=O
Formula: C24H19NO7S
Pathway: Metabolism
Target: Dehydrogenase
Receptor: N/A
Bioactivity: CVT-10216 is a Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50: 29 nM). CVT-10216 also has inhibitory effect of ALDH-1 (IC50: 1.3 μM). CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects.
Molecular Weight: 465, 48
