Product Overview
Cycloguanil hydrochloride | T5420 | TargetMol Chemicals
CAS: 152-53-4
Smiles: Cl.CC1(C)N=C(N)N=C(N)N1c1ccc(Cl)cc1
Formula: C11H15Cl2N5
Pathway: Metabolism|||Microbiology/Virology
Target: Parasite|||Drug Metabolite
Receptor: N/A
Bioactivity: Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms, respectively).
Molecular Weight: 288, 18
