Product Overview
Cyclopamine | T2825 | TargetMol Chemicals
CAS: 4449-51-8
Smiles: C[C@@H]1[C@@H]2NC[C@@H](C)C[C@H]2O[C@]11CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC2=C1C
Formula: C27H41NO2
Pathway: GPCR/G Protein|||Metabolism|||Stem Cells
Target: Hedgehog/Smoothened|||Endogenous Metabolite|||Smo
Receptor: N/A
Bioactivity: Cyclopamine, a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids.
Molecular Weight: 411, 63
