Product Overview
Cyclosporin H | T21493 | TargetMol Chemicals
CAS: 83602-39-5
Smiles:
Formula: N/A
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Cyclosporin H (CsH), a specific inhibitor of FPR1, inhibited lung inflammation in the ALI models. CsH significantly attenuated MTDs or NFP-induced inflammatory lung injury and activation of MAPK and AKT pathways. Cyclosporin H is a viral transduction enhancer which increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). When combined with Rapamycin or Prostaglandin E2 Cyclosporin H displays an additive effect. Cyclosporin H lacks immunosuppressant activity of Cyclosporin A.
Molecular Weight: N/A
