Product Overview
Cyclotraxin B | TP2068 | TargetMol Chemicals
CAS: 1203586-72-4
Smiles:
Formula: C48H73N13O17S3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also shown to exhibit putative anxiolytic properties in mice.
Molecular Weight: 1200, 36
