Product Overview
CZC-54252 hydrochloride | T39202 | TargetMol Chemicals
CAS: 1784253-05-9
Smiles: Cl.O=S(=O)(NC=1C=CC=CC1NC2=NC(=NC=C2Cl)NC3=CC=C(C=C3OC)N4CCOCC4)C
Formula: C22H26Cl2N6O4S
Pathway: Autophagy
Target: LRRK2
Receptor: N/A
Bioactivity: CZC-54252 hydrochloride is a selective inhibitor of LRRK2 with IC50s of 1.85 nM and 1.28 nM for wild-type and G2019S LRRK2. CZC-54252 hydrochloride has a neuroprotective activity and attenuates G2019S LRRK2-induced human neuronal injury with an EC50 of 1 nM.
Molecular Weight: 541, 45
