Product Overview
D5D-IN-326 | T15043 | TargetMol Chemicals
CAS: 1236767-85-3
Smiles: FC(F)(F)COc1ccc(cc1)-n1c(OCC(F)(F)C(F)(F)F)nc2NC(=O)Cc2c1=O
Formula: C17H11F8N3O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: D5D-IN-326 is an orally active delta-5 desaturase (D5D) inhibitor (IC50s: 72 and 22 nM for rat and human D5D in enzymic and cell-based assays). It has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice.
Molecular Weight: 473, 279
