Product Overview
DA-6886 | T27117 | TargetMol Chemicals
CAS: 1645260-76-9
Smiles: Cl.COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CCCn2ccnn2)CC1
Formula: C19H28Cl2N6O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressing hERG channels revealed that it inhibited hERG channel current with an pIC50 value of 4.3, indicating that the compound was 1000-fold more selective for the 5-HT4 receptor over hERG channels.
Molecular Weight: 443, 37
