Product Overview
Dactolisib | T2235 | TargetMol Chemicals
CAS: 915019-65-7
Smiles: Cn1c2cnc3ccc(cc3c2n(-c2ccc(cc2)C(C)(C)C#N)c1=O)-c1cnc2ccccc2c1
Formula: C30H23N5O
Pathway: Autophagy|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Target: ATM/ATR|||PI3K|||mTOR|||Autophagy
Receptor: N/A
Bioactivity: Dactolisib is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).
Molecular Weight: 469, 548
