Product Overview
Dactolisib Tosylate | T14552 | TargetMol Chemicals
CAS: 1028385-32-1
Smiles: Cc1ccc(cc1)S(O)(=O)=O.Cn1c2cnc3ccc(cc3c2n(-c2ccc(cc2)C(C)(C)C#N)c1=O)-c1cnc2ccccc2c1
Formula: C37H31N5O4S
Pathway: Autophagy|||PI3K/Akt/mTOR signaling
Target: PI3K|||mTOR|||Autophagy
Receptor: N/A
Bioactivity: Dactolisib Tosylate (BEZ235 Tosylate) is an inhibitor of dual PI3K and mTOR kinase(IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively). Dactolisib Tosylate also inhibits mTORC1 and mTORC2.
Molecular Weight: 641, 75
