Product Overview
Danusertib | T2094 | TargetMol Chemicals
CAS: 827318-97-8
Smiles: CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1n[nH]c2c1CN(C2)C(=O)[C@@H](c1ccccc1)OC
Formula: C26H30N6O3
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: FGFR|||Trk receptor|||c-RET|||Bcr-Abl|||Aurora Kinase|||Autophagy
Receptor: N/A
Bioactivity: Danusertib is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Danusertib binds to and inhibits the Aurora kinases, which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpressed.
Molecular Weight: 474, 55
