Product Overview
Daphnetin | T2851 | TargetMol Chemicals
CAS: 486-35-1
Smiles: Oc1ccc2ccc(=O)oc2c1O
Formula: C9H6O4
Pathway: Angiogenesis|||Autophagy|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||JAK/STAT signaling|||Microbiology/Virology|||Tyrosine Kinase/Adaptors
Target: EGFR|||PKA|||PKC|||Parasite|||Autophagy
Receptor: N/A
Bioactivity: Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-inflammatory activities.
Molecular Weight: 178, 143