Product Overview
DAPT | T6202 | TargetMol Chemicals
CAS: 208255-80-5
Smiles: C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@H](C(=O)OC(C)(C)C)c1ccccc1
Formula: C23H26F2N2O4
Pathway: Apoptosis|||Autophagy|||Neuroscience|||Proteases/Proteasome|||Stem Cells
Target: Apoptosis|||Beta Amyloid|||Gamma-secretase|||Autophagy
Receptor: N/A
Bioactivity: DAPT is a novel γ-secretase inhibitor which reduces the Aβ production (IC50: 20 nM in HEK 293 cells) and Aβ42 levels (IC50: 200 nM).
Molecular Weight: 432, 468
