Product Overview
Dauricine | T6S0119 | TargetMol Chemicals
CAS: 524-17-4
Smiles: COc1cc2CCN(C)[C@H](Cc3ccc(Oc4cc(C[C@H]5N(C)CCc6cc(OC)c(OC)cc56)ccc4O)cc3)c2cc1OC
Formula: C38H44N2O6
Pathway: Apoptosis|||NF-Κb|||Others
Target: Apoptosis|||Others|||NF-κB
Receptor: N/A
Bioactivity: 1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profile of its downstream genes.
Molecular Weight: 624, 778
