Daurinoline | T2S0118

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€1,095.00
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TMC-T2S0118
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Product Overview

Daurinoline | T2S0118 | TargetMol Chemicals

CAS: 2831-75-6

Smiles: COc1cc2[C@@H](Cc3ccc(Oc4cc(C[C@H]5N(C)CCc6cc(OC)c(OC)cc56)ccc4O)cc3)N(C)CCc2cc1O

Formula: C37H42N2O6

Pathway: GPCR/G Protein|||Immunology/Inflammation|||Membrane transporter/Ion channel|||Metabolism|||Neuroscience

Target: Calcium Channel|||5-HT Receptor|||Histamine Receptor

Receptor: N/A

Bioactivity: Daurinoline is a non-competitive antagonist, it exerts marked relaxation effect on basilar artery of rabbits through non-competitive antagonism, it would have a protective function on microcirculation of cerebral pia mater, which may be beneficial to relieve cerebral ischemic injury. Daurinoline could significantly reverse noradrenaline induced constriction of pial arterioles and venules, and increase the number of blood vessels which were decreased by noradrenaline.

Molecular Weight: 610, 75

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