Product Overview
DBCO-PEG4-Ahx-DM1 | T17793 | TargetMol Chemicals
CAS: T17793
Smiles: COC1=CC(C/C(C)=C/C=C/[C@@H](OC)[C@]2(O)NC(OC([C@@H](C)C(O3)[C@]3(C)[C@@H](OC([C@H](C)N(C)C(CCCCCNC(CCOCCOCCOCCOCCNC(CCC(N4CC(C=CC=C5)=C5C#CC6=C4C=CC=C6)=O)=O)=O)=O)=O)CC7=O)C2)=O)=CC(N7C)=C1Cl
Formula: C68H89ClN6O17
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.
Molecular Weight: 1297, 92
