Product Overview
dBET6 | T5130 | TargetMol Chemicals
CAS: 1950634-92-0
Smiles: Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)NCCCCCCCCNC(=O)COc1cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c13)c1nnc(C)n-21)c1ccc(Cl)cc1
Formula: C42H45ClN8O7S
Pathway: Apoptosis|||Chromatin/Epigenetic
Target: Apoptosis|||Epigenetic Reader Domain
Receptor: N/A
Bioactivity: dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.
Molecular Weight: 841, 38