DCB-3503 | T27128

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TMC-T27128
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Product Overview

DCB-3503 | T27128 | TargetMol Chemicals

CAS: 87302-58-7

Smiles: [H][C@@]12CCCN1Cc1c([C@@H]2O)c2cc(OC)c(OC)cc2c2cc(OC)c(OC)cc12

Formula: C24H27NO5

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: Tylophorine analog DCB-3503 is a potential anticancer and immunosuppressive agent. DCB-3503 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. DCB-3503 allosterically regulates the ATPase and chaperone activities of HSC70 by promoting ATP hydrolysis in the presence of specific RNA binding motifs (AUUUA) of cyclin D1 mRNA.

Molecular Weight: 409, 482

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