Product Overview
Decernotinib | T2636 | TargetMol Chemicals
CAS: 944842-54-0
Smiles: CC[C@](C)(C(=O)NCC(F)(F)F)Nc1nc(ncc1)c1c[nH]c2c1cccn2
Formula: C18H19F3N6O
Pathway: Angiogenesis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: Tyrosine Kinases|||JAK
Receptor: N/A
Bioactivity: Decernotinib(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.
Molecular Weight: 392, 38