Product Overview
Defactinib hydrochloride | T15092 | TargetMol Chemicals
CAS: 1073160-26-5
Smiles: Cl.CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1
Formula: C20H22ClF3N8O3S
Pathway: Angiogenesis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: FAK
Receptor: N/A
Bioactivity: Defactinib hydrochloride is a novel inhibitor of FAK which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.
Molecular Weight: 546, 95