Product Overview
Degrasyn | T6300 | TargetMol Chemicals
CAS: 856243-80-6
Smiles: CCC[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1
Formula: C19H18BrN3O
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||DNA Damage/DNA Repair|||Tyrosine Kinase/Adaptors|||Ubiquitination
Target: Apoptosis|||Bcr-Abl|||DUB|||Autophagy
Receptor: N/A
Bioactivity: Degrasyn (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT).
Molecular Weight: 384, 277